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Disruption of a Yeast ADE6 Gene Homolog in Ustilago maydis

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Abstract

A putative homolog of the Sacharromyces cereviseae ADE6 and Escherichia coli purL genes is identified near a multigenic complex, which contains two genes, sid1 and sid2, involved in a siderophore biosynthetic pathway inUstilago maydis. The putative ADE6 homolog was mutated by targeted gene disruption. The resulting mutant strains demonstrated a requirement for exogenous adenine, indicating that the U. maydis ade6 homolog is required for purine biosynthesis.

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Heidenreich, M. L., Budde, A. D., Zhiqiang, A. & Leong, S. A., (2008) “Disruption of a Yeast ADE6 Gene Homolog in Ustilago maydis”, Fungal Genetics Reports 55(1), 40-43. doi: https://doi.org/10.4148/1941-4765.1090

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Published on
2008-12-01