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Predicting the Identities of su(met-2) and met-3 in Neurospora crassa by Genome Resequencing

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Abstract

A significant number of classical genetic Neurospora crassa biochemical mutants remain anonymous, unassociated with a physical genome locus. By utilizing short read next-generation sequencing methods, it is possible to sequence the genomes of mutant strains rapidly and economically for the purpose of identifying genes associated with mutant phenotypes. We have taken this approach to connect genes and mutations to “methionineless” phenotypes in N. crassa.

Keywords: Neurospora, genome resequencing, methionine, cysteine, metabolism, mutants

How to Cite:

McCluskey, K., Brown, D., Bredeweg, E. & Baker, S. E., (2024) “Predicting the Identities of su(met-2) and met-3 in Neurospora crassa by Genome Resequencing”, Fungal Genetics Reports 67(1). doi: https://doi.org/10.4148/1941-4765.2183

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Published on
2024-02-01