Abstract
Although most eukaryotes have both MSH4 and MSH5 orthologs, Neurospora was initially thought to lack msh-4. We have deleted the most likely msh-4 candidate and observed a delay in the sexual cycle, disruption to meiosis and a reduction in fertility. Deletion is dominant, showing msh-4 is subject to MSUD. We conclude that Neurospora has a MSH4 ortholog and that it may have remained undetected because of an unusually high number of introns.
How to Cite:
Conway, S., Bowring, F., Yeadon, J. & Catcheside, D., (2006) “Neurospora msh4 ortholog confirmed by split-marker deletion”, Fungal Genetics Reports 53(1), 5-8. doi: https://doi.org/10.4148/1941-4765.1105
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