Abstract
Objective:This study was conducted to evaluate the effects of supplemental choline in combination with guanidinoacetic acid or creatine on immune cell function and inflammation in growing cattle.
Study Description:Six ruminally-cannulated Holstein steers (321 lb) were utilized in an experiment where each steer received each of six treatments. Treatments were given via abomasal infusion of a 0 or 5 g/day of supplemental choline, and either a saline solution (control); 15 g/day guanidinoacetic acid; or 16.8 g/day of creatine, with all treatment combinations represented. Steers were fed a corn-based diet. Blood was collected during each period to measure neutrophil function, plasma haptoglobin, and plasma antioxidant potential.
Bottom line:Supplementing steers with 5 g/day of choline tended to reduce plasma haptoglobin concentrations, suggesting that choline reduced systemic inflammation.
Keywords: methyl groups, choline, immune function
How to Cite:
Grant, M. S., Aufdemberge, H. D., Bradford, B. J., Mamedova, L. K. & Titgemeyer, E. C., (2021) “Effects of Choline on Neutrophil Function and Inflammation in Growing Cattle with Modulated Methyl Group Status”, Kansas Agricultural Experiment Station Research Reports 7(1). doi: https://doi.org/10.4148/2378-5977.8033
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