Abstract

A total of 270 pigs from 29 litters (PIC 327 × 1050, initially 2 d of age) were used in a 52-d study to determine the effects of oral vitamin D3 supplementation on growth performance, serum 25(OH)D3 concentrations, and bone mineralization of pre- and postweaning pigs. Vitamin D plays an essential role in maintaining proper Ca and P homeostasis within the body of mammals. Because most swine production occurs in environmentally controlled facilities, direct sunlight is no longer a source of vitamin D for the neonatal pig, which could impact bone growth and muscle function. Experimental treatments consisted of 3 oral dosage treatments: (1) control (1 mL peanut oil), (2) 40,000 IU vitamin D3 delivered in 1 mL peanut oil, or (3) 80,000 IU vitamin D3 delivered in 1 mL peanut oil. Pigs were initially weighed over 2 differ- ent days (d 0 or 2), allowing pigs to be placed on test 1 or 2 d after birth. Within a litter, pigs were assigned to similar-weight matched sets of 3 and were allotted to 1 of the 3 oral dosage treatments. Blood samples were collected from pigs of 29 matched sets (87 pigs total) prior to dosing, then the same matched set pigs were bled periodi- cally throughout the trial to measure 25(OH)D3 serum concentrations. All pigs were weighed again on d 10 and 20. On d 20, pigs were weaned and allotted to the nursery portion of the trial and all pigs were fed common diets from d 20 to 52 of age. Pigs were also randomly selected for necropsy on d 19 and d 35. Eighteen pigs were necropsied on d 19 (6 matched sets for a total of 6 pigs per treatment) and 12 pigs were necropsied on d 35 (6 control pigs and 6 pigs previously dosed with 80,000 IU vitamin D3). Bone and tissue samples were collected. All bone samples were analyzed for ash content and histopathology.; Swine Day, Manhattan, KS, November 17, 2011

Keywords: Swine Day, 2011, Kansas Agricultural Experiment Station contribution, no. 12-064-S, Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service), 1056, Swine, Nursery pig, Vitamin D, 25(OH)D3

How to Cite:

Flohr, J. R., Tokach, M. D., Henry, S. C., Potter, M. L., Tokach, L. M., Goff, J. P., Horst, R. L., Nietfeld, J. C., Madson, D. M., Ensley, S. M., Bergstrom, J. R., DeRouchey, J. M., Goodband, R. D., Nelssen, J. L. & Dritz, S. S., (2011) “The effects of orally supplemented vitamin D3 on serum 25(OH)D3 concentrations and growth of pre-weaning and nursery pigs”, Kansas Agricultural Experiment Station Research Reports 1(10), 34-45. doi: https://doi.org/10.4148/2378-5977.7144